Publications

Circulating Tumor Cells

  • Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination | Read More
  • HER2 expression identifies dynamic functional states within circulating breast cancer cells | Read More
  • Characterization of PD-L1 expression on circulating tumor cells (CTCs) isolated with a label-free inertial microfluidic system from advanced non-small cell lung cancer patients (NSCLC pts)| Read More
  • Inertial Focusing for Tumor Antigen Dependent and Independent Sorting of Rare Circulating Tumor Cells | Read More
  • A prospective evaluation of circulating tumor cells and cell-free DNA in EGFR mutant non-small cell lung cancer patients treated with erlotinib on a phase II trial| Read More
  • Immunohistochemistry in the Study of Cancer Biomarkers for Oncology Drug Development | Read More
  • Tunable Nanostructured Coating for the Capture and Selective Release of Viable Circulating Tumor Cells | Read More
  • Bioengineered implantable scaffolds as a tool to study stromal-derived factors in metastatic cancer models | Read More
  • A microfluidic device for label-free, physical capture of circulating tumor cell clusters | Read More
  • The Identification and Characterization of Breast Cancer CTCs Competent for Brain Metastasis | Read More
  • MAPK7 regulates EMT Features and Modulates the Generation of CTCs | Read More
  • Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells | Read More
  • Circulating Tumor Cells: A Multifunctional Biomarker | Read More
  • Androgen Receptor Signaling in Circulating Tumor Cells as a Marker of Hormonally Responsive Prostate Cancer | Read More
  • Genetically Abnormal Circulating Cells in Lung Cancer Patients: An Antigen-Independent Fluorescence In situ Hybridization–Based Case-Control Study | Read More
  • Circulating Tumor Cells Are Transcriptionally Similar to the Primary Tumor in a Murine Prostate Model | Read More
  • Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches | Read More
  • A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker | Read More

Pathology:

  • Breast Cancer Biomarkers Before and After Neoadjuvant Chemotherapy: Does Repeat Testing Impact Therapeutic Management? | Read More
  • Vulvar and vaginal melanoma: A unique subclass of mucosal melanoma based on a comprehensive molecular analysis of 51 cases compared with 2253 cases of nongynecologic melanoma | Read More
  • Utilization of Innovative Web Based FISH Review and Analysis Solution in Daily Clinical Practice | Read More
  • Testing for ROS1 in non-small cell lung cancer: a review with recommendations | Read More
  • Precision medicine in NSCLC and pathology: how does ALK fit in the pathway? | Read More
  • Genomic alterations in neuroendocrine cancers of the ovary | Read More
  • Genomic landscape of small cell carcinoma of the breast contrasted to small cell carcinoma of the lung | Read More
  • Clinical Significance of “Double-hit” and “Double-protein” expression in Primary Gastric B-cell Lymphomas | Read More
  • Profile of Ventana ALK (D5F3) companion diagnostic assay for non-small-cell lung carcinomas | Read More
  • Definition of MYC genetic heteroclonality in diffuse large B-cell lymphoma with 8q24 rearrangement and its impact on protein expression | Read More
  • ALK Protein Analysis by IHC Staining after Recent Regulatory Changes: A Comparison of Two Widely Used Approaches, Revision of the Literature, and a New Testing Algorithm | Read More
  • Materials and methods for assessing progression of prostate cancer | Read More
  • Molecular profiling of head and neck squamous cell carcinoma | Read More
  • The anaplastic lymphoma kinase testing Conundrum  | Read More
  • ALK testing in lung adenocarcinoma: technical aspects to improve FISH evaluation indaily practice | Read More
  • Accurate Identification of ALK Positive Lung Carcinoma Patients: Novel FDA-Cleared Automated Fluorescence In Situ Hybridization Scanning System and Ultrasensitive Immunohistochemistry | Read More
  • Computerized Analysis of Cytology and Fluorescence In Situ Hybridization (FISH) in Induced Sputum for Lung Cancer Detection | Read More
  • Automation of ALK gene rearrangement testing with fluorescence in situ hybridization (FISH): a feasibility study | Read More
  • The t(14;18)(q32;q21)/IGH–MALT1 translocation in gastrointestinal extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) | Read More
  • Tumor derived vasculogenesis in von Hippel-Lindau disease-associated tumors | Read More
  • Oral lichen planus patients exhibit consistent chromosomal numerical aberrations: A follow-up analysis | Read More
  • Expression of human epidermal growth factor receptor 2 in primary and paired parenchymal recurrent and/or metastatic sites of gastric cancer | Read More
  • CDK4 amplification reduces sensitivity to CDK4/6 inhibition in fusion-positive rhabdomyosarcoma | Read More
  • Sequential phenotype/genotype FISH assay targeting rare tumor cells using archived bone marrow smears and paraffin embedded tissue sections | Read More
  • Human Barrett’s Adenocarcinoma of the Esophagus, Associated Myofibroblasts, and Endothelium Can Arise from Bone Marrow-Derived Cells After Allogeneic Stem Cell Transplant | Read More
  • Cytology Specimens Offer an Effective Alternative to Formalin-Fixed Tissue as Demonstrated by Novel Automated Detection for ALK Break-Apart FISH Testing and Immunohistochemistry in Lung Adenocarcinoma | Read More
  • ERG expression in epithelioid sarcoma: a diagnostic pitfall | Read More
  • Accurate assessment of HER2 status in “triple-negative” breast cancer requires both IHC and FISH testing | Read More
  • Cholangiocarcinoma in a 17-year-old boy with primary sclerosing cholangitis and UroVysion™ fluorescent in situ hybridization | Read More
  • Identification by array comparative genomic hybridization of a new amplicon on chromosome17q highly recurrent in BRCA1 mutated triple negative breast cancer | Read More
  • Bioview Duet – Assisted Fluorescence In Situ Hybridization for Gastrointestinal Malignancy | Read More
  • Molecular Pathology , a practical guide for the surgical pathologist and cytopathologist | Read More
  • Chromosomal numerical aberrations in apparently normal oral mucosa of heavy smokers affected by lung cancer | Read More
  • Noninvasive detection of aneuploid cells in laryngeal epithelial precursor lesions | Read More
  • Oral lichen planus patients exhibit consistent chromosomal numerical aberrations: A follow-up analysis | Read More

Bladder

  • Role of Tetrasomy for the Diagnosis of Urothelial Carcinoma Using UroVysion Fluorescent In Situ Hybridization | Read More
  • Ancillary Studies in Urinary Cytology | Read More
  • A retrospective review of UroVysion fish interpretations over 8.6 years: a major shift in the patient test population | Read More
  • Integrating a FISH imaging system into the cytology laboratory | Read More
  • Validation and Clinical Utility Assessment of an Automated Capture/Analysis System for FISH to Detect Urothelial Carcinoma | Read More
  • Target UroVysion FISH for Urinary Specimens Using FISH for Urinary Specimens Using the Duet the Duet Imaging System | Read More
  • Guidelines for Pancreaticobiliary Cytology from the Papanicolaou Society of Cytopathology: A Review | Read More
  • ‘‘FISHing’’ to Detect Urinary and Other Cancers | Read More
  • FISHING to detect urinary and other cancers: do imaging systems help? | Read More
  • Combined analysis of morphology and fluorescence in situ hybridization significantly increases accuracy of bladder cancer detection in voided urine samples | Read More

Target FISH

  • Target fluorescence in-situ hybridization (Target FISH) for plasma cell enrichment in myeloma | Read More
  • Characterizing T Cells in SCID Patients Presenting with Reactive or Residual T Lymphocytes | Read More
  • Multilineage hematopoietic engraftment after allogeneic peripheral blood stem cell transplantation without conditioning in SCID patients | Read More
  • Co-existence of clonal expanded autologous and transplacental-acquired maternal T cells in recombination activating gene-deficient severe combined immunodeficiency | Read More
  • Characterization of bone marrow mast cells in acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1 | Read More
  • MUC1 Is a Potential Target for the Treatment of Acute Myeloid Leukemia Stem Cells | Read More
  • Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components | Read More
  • Trisomy 8 in B-cell chronic lymphocytic leukemia | Read More
  • Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic clone | Read More
  • Fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma | Read More
  • Megakaryocytic blast crisis as a presenting manifestation of chronic myeloid leukemia | Read More
  • Targeting plasma cells improves detection of cytogenetic aberrations in multiple myeloma: phenotype/genotype fluorescence in situ hybridization | Read More
  • Morphology assessment and fluorescence in situ hybridization of the same spermatozoon using a computerized cell-scanning system | Read More
  • Ploidy of spermatogenic cells of men with non-mosaic Klinefelter’s syndrome as measured by a computerized cell scanning system | Read More
  • Combined analysis of morphology and fluorescence in situ hybridization in follow-up of minimal residual disease in a child with Philadelphia-positive acute lymphoblastic leukemia | Read More
  • Chimerism testing and detection of minimal residual disease after allogeneic hematopoietic transplantation using the BioView (Duet) combined morphological and cytogenetical analysis | Read More
  • Tetraploid myeloid cells in donors of peripheral blood stem cells treated with rhG-CSF | Read More
  • The multiparametric scanning system for evaluation of minimal residual disease in hematological malignancies | Read More
  • Determination of chromosome 13 status in bone marrow cells of patients with multiple myeloma using combined morphologic and fluorescence in situ hybridization analysis | Read More
  • Co-existence of multiple subclones in TEL-AML1 at diagnosis of acute lymphoblastic leukaemia in association with submicroscopic deletion of AML1 | Read More
  • Philadelphia-chromosome-positive T-lymphoblastic leukemia: acute leukemia or chronic myelogenous leukemia blastic crisis | Read More
  • Clonal expansion of a new MLL rearrangement in the absence of leukemia | Read More
  • Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease | Read More
  • Detection of non-diploid cells in premalignant and malignant oral lesions using combined morphological and FISH analysis – a new method for early detection of suspicious oral lesions | Read More
  • Chromosome 13q deletion and IgH abnormalities may be both masked by near-tetraploidy in a high proportion of multiple myeloma patients: a combined morphology and I-FISH analysis | Read More
  • Could rhG-CSF induction of tetraploidy contribute to leukemogenesis in healthy donors? | Read More
  • Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient | Read More
  • Post-essential thrombocythemia myelofibrosis and chronic myelomonocytic leukemia can co-exist with complex cytogenetic abnormalities  | Read More
  • Correlation between losses of IGH or its segments and deletions of 13q14 in t(11;14) (q13;q32) multiple myeloma | Read More
  • Combined simultaneous analysis of morphology and fluorescence in situ hybridization as a novel sensitive method for detecting small populations of malignant cells in patients with a high risk of cancer, premalignant lesions and minimal residual disease | Read More

Others:

  • BioView President and CEO interview at ILTV| Watch Video Clip
  • A case of Philadelphia chromosome positive acute lymphoblastic leukemia with partial trisomy of chromosome 1q involving chromosome 13 as the acceptor − a novel cytogenetic finding| Read More
  • In Situ Hybridization in Clinical Biomarker Development | Read More
  • FGFR3 Preferentially Colocalizes with IGH in the Interphase Nucleus of Multiple Myeloma Patient
    B-Cells When FGFR3 Is Located Outside of CT4 | Read More
  • MLL: The Gene and Its Translocation Partners. 2 Cases with a t(11;17) Involving MLL and Mimicking the Variant t(11;17) RARA Translocation | Read More
  • Testicular versus ejaculated spermatozoa in ICSI cycles of normozoospermic men with high sperm DNA fragmentation and previous ART failures | Read More
  • A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant Women | Read More
  • An Overview on Prenatal Screening for Chromosomal Aberrations | Read More
  • Canine urothelial carcinoma: genomically aberrant and comparatively relevant | Read More
  • Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization | Read More